Molecular pathology in clinical practice pdf

Leavitt, and a past President of the Association for Molecular Pathology. She has spoken widely on various molecular pathology test services, the future of molecular diagnostics and the impact of gene patents on molecular pathology practice and patient access to molecular diagnostic testing services. Most recently, Dr. Leonard was honored by receiving the Leadership Award from the Association for Molecular Pathology. It also will be useful to surgical and clinical pathologists, hematologists, oncologists, internists, scientists who undertake disease-related basic science and translational research, and medical laboratory technologists.

Skip to main content Skip to table of contents. Advertisement Hide. This service is more advanced with JavaScript available. Molecular Pathology in Clinical Practice. Editors view affiliations Debra G. Fully updated and largely rewritten new edition Written by experts in the field Provides a comprehensive, state-of-the art review of the field of molecular pathology Includes supplementary material: sn.

Front Matter Pages i-xix. Basics of Molecular Biology. Pages Molecular Pathology Methods. Hunter Best, Shale A. Sumner, Cecily P. Vaughn et al. Front Matter Pages In addition, new molecular techniques are entering the clinical arena for their value in predicting therapy response and tumor prognosis.

The book is organized by anatomical systems and provides a detailed description of molecular tests that may help in the diagnosis. Furthermore, a description of the current molecular tests required to identify patients for treatment is offered. The application of molecular pathology techniques to the clinical practice has already shown its usefulness and the number of such tests is growing exponentially as more molecular targets are discovered.

Molecular Pathology and Diagnostics of Cancer will give practicing and training pathologists an up-to date resource to guide the correct management of pathology cases requiring molecular testing.

Author : Sunil R. Lakhani Publisher: Springer ISBN: Category: Medical Page: View: Read Now » The aim of the book is to discuss the application of molecular pathology in cancer research, and its contribution in the classification of different tumors and identification of potential molecular targets, as well as how this knowledge may be translated into clinical practice, and the huge impact this field is likely to have in the next 5 to 10 years.

Author : Jennifer L. Mole- lar diagnostics, molecular targeted therapy, and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners , clinical inves- gators, pathologists and medical laboratory directors, and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis, and treatment for their patients.

Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology.

Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice. While this textbook focuses on molecular and genomic testing, with only a single chapter covering proteomics, the reader must understand that the genome does not drive all disease and health, but works in concert with the environment, the metabolome, the methylome, and other determinants of disease and health.

As we move toward genomic medicine, the molecular pathologist and all pathologists will play a signifi cant role in the proper utilization of molecular and genomic tests to improve patient outcomes and the cost-effectiveness of the care we deliver. In the era of US healthcare reform, the promise of genomic medicine aligns almost perfectly with the healthcare reform goals of improving individual patient outcomes, improving the health of populations, and reducing the cost of healthcare.

While much of genomic research focuses on the clinical signifi cance of pathogen and patient genomic variants for diagnosis and therapy, evidence of the value of genomics in clinical care also is needed, especially as we move toward population health management and global payment models.

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